Name: Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: Southern
Ingredients: 12 oz penne pasta; 1 lb ground beef; 1½ cups Velveeta cheese, cubed; 1 cup heavy cream; 1 tablespoon Cajun seasoning; 2 cloves garlic, minced; 1 tablespoon butter; 2 tablespoons chopped parsley or green onions (optional, for garnish); Salt and pepper, to taste

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Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce is a bold and comforting Southern-inspired pasta dish that’s ready in just 30 minutes. Featuring penne pasta smothered in a rich, velvety Alfredo sauce made with Velveeta cheese and Cajun-seasoned ground beef, this dish is packed with flavor and hearty enough to satisfy any appetite. It’s perfect for busy weeknights, casual family dinners, or anyone craving creamy, cheesy goodness with a little kick.

Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

Why You’ll Love This Recipe

This recipe delivers the kind of comfort that only a creamy pasta dish can, with the bonus of Cajun-spiced beef to add depth and a touch of heat. The Velveeta cheese melts into the cream for a silky-smooth sauce, while the penne perfectly holds all that rich flavor in every bite. It’s fast, simple, affordable, and guaranteed to be a hit whether you’re cooking for the family or meal prepping for the week.

Ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

12 oz penne pasta
1 lb ground beef
1½ cups Velveeta cheese, cubed
1 cup heavy cream
1 tablespoon Cajun seasoning
2 cloves garlic, minced
1 tablespoon butter
2 tablespoons chopped parsley or green onions (optional, for garnish)
Salt and pepper to taste

Directions

Bring a medium pot of salted water to a boil. Add penne and cook until al dente according to package instructions. Drain and set aside.
In a large skillet, melt the butter over medium heat. Add ground beef and cook until browned and fully cooked, breaking it apart as it cooks. Drain excess grease.
Add the minced garlic and Cajun seasoning to the skillet. Cook for about 1 minute until fragrant.
Pour in the heavy cream and stir to combine. Gradually add the Velveeta cheese cubes, stirring constantly until the sauce is smooth and creamy.
Add the cooked penne pasta to the skillet and gently toss to coat in the cheesy sauce. Simmer on low for 2–3 minutes to let the flavors come together.
Garnish with chopped parsley or green onions if desired. Serve hot.

Servings and timing

This recipe yields 4 servings.
Prep time: 10 minutes
Cook time: 20 minutes
Total time: 30 minutes

Variations

Lighter Version: Use ground turkey or plant-based crumbles instead of beef.
Extra Spicy: Add a pinch of red pepper flakes or an extra dash of Cajun seasoning for more heat.
Veggie Add-In: Stir in sautéed bell peppers, spinach, or mushrooms to add texture and nutrients.
Different Pasta: Try rotini, rigatoni, or shells for a different twist.
Double Cheese: Mix in a little shredded cheddar or pepper jack for a bolder flavor blend.

Storage/Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days.
To reheat, warm in a skillet over low heat or in the microwave, adding a splash of milk or cream to restore creaminess and prevent the sauce from thickening too much.

FAQs

Can I use another type of cheese instead of Velveeta?

Yes, but Velveeta melts exceptionally well for a smooth, creamy sauce. Shredded cheddar or American cheese are good alternatives, though they may result in a slightly different texture.

Is Cajun seasoning very spicy?

It’s usually mildly spicy with a smoky, savory flavor. You can adjust the amount based on your heat preference.

Can I use half-and-half instead of heavy cream?

Yes, though the sauce may be slightly less rich. Add a bit of butter to compensate for the lower fat content.

What type of ground meat works best?

Ground beef provides a hearty base, but ground turkey, chicken, or vegetarian crumbles can be used as well.

Can I make this ahead of time?

Yes. You can prepare the dish, store it in the fridge, and reheat it later with a splash of cream or milk.

Does this freeze well?

Cream-based sauces can separate when frozen and reheated, so it’s best enjoyed fresh or refrigerated rather than frozen.

Can I make it gluten-free?

Yes, simply substitute the penne with your favorite gluten-free pasta and ensure all other ingredients are certified gluten-free.

What can I serve with this pasta?

It pairs well with a fresh green salad, garlic bread, or roasted vegetables.

Can I make it without garlic?

Yes, but the garlic adds great flavor. You could substitute with garlic powder or leave it out entirely if needed.

How do I keep the sauce from getting too thick?

Add a small amount of reserved pasta water or milk if the sauce thickens too much after sitting or during reheating.

Conclusion

Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce is a rich, satisfying meal that combines Southern spice with classic comfort food. The blend of Cajun-seasoned beef and silky cheese sauce tossed with pasta creates a dish that’s bold, easy, and guaranteed to please. Whether it’s a busy weeknight or you’re cooking to impress, this flavorful pasta is sure to hit the spot.